Research Interests
Development of advanced materials with unique electronic, optical, structural, or interfacial properties; development of efficient manufacturing processes for the biotechnology industry.
Education
- Ph.D.: Chemical Engineering, (1990), University of Connecticut - Storrs, Conn.
Dissertation/Thesis Title: Biological Production of Nonlinear Optical Materials - MS: Chemical Engineering, (1985), University of Connecticut - Storrs, Conn.
- MS: Microbiology, (1977), University of Connecticut - Storrs, Conn.
- BS: Microbiology, (1972), Purdue University - West Lafayette, Ind.
Selected Awards and Honors
- State of Connecticut High Technology Fellowship (1984)
Selected Publications
- Ding, E., Ensom, E., Hafer, N., Buchholz, B., Picard, M., Dunlap, D., Rogers, E., Lawton, C., Koren, A., Lilly, C., Fitzgibbons, T., McManus, D. (2019). Point-of-care technologies in heart, lung, blood and sleep disorders from the Center for Advancing Point-of-Care Technologies. Current Opinion in Biomedical Engineering, 11 58-67.
- Lee, H., Lawton, C.W., Na, Y., Yoon, S. (2013). Robustness of chemometrics-based feature selection methods in early cancer detection and biomarker discovery. Statistical Applications in Genetics and Molecular Biology, 12(2) 207-223.
- Nicolosi, R.J., Wilson, T.A., Lawton, C.W., Handelman, G.J. (2001). Dietary effects on cardiovascular disease risk factors: Beyond saturated fatty acids and cholesterol. Journal of the American College of Nutrition, 20(5) 421-427.
- Wilson, T.A., Ausman, L.M., Lawton, C.W., Hegsted, D.M., Nicolosi, R.J. (2000). Comparative cholesterol lowering properties of vegetable oils: Beyond fatty acids. Journal of the American College of Nutrition, 19(5) 601-607.
- Wilson, T.A., Nicolosi, R.J., Lawton, C.W., Babiak, J. (1999). Gender differences in response to a hypercholesterolemic diet in hamsters: Effects on plasma lipoprotein cholesterol concentrations and early aortic atherosclerosis. Atherosclerosis, 146(1) 83-91.
- Lawton, C.W., Swartz, R. (1999). Process for the Purification of Acarbose, Pharmaceutical Composition Containing Same and its Use for the Treatment of Diabetes.
- Nicolosi, R.J., Lawton, C.W., Wilson, T.A. (1999). Vitamin E reduces plasma low density lipoprotein cholesterol, LDL oxidation, and early aortic atherosclerosis compared with black tea in hypercholesterolemic hamsters. Nutrition Research, 19(8) 1201-1214.
- Nicolosi, R.J., Wilson, T.A., Lawton, C.W., Rogers, E.J., Wiseman, S.A., Tijburg, L.B., Kritchevsky, D. (1998). The greater atherogenicity of nonpurified diets versus semipurified diets in hamsters is mediated via differences in plasma lipoprotein cholesterol distribution, ldl oxidative susceptibility, and plasma α-tocopherol concentration. Journal of Nutritional Biochemistry, 9(10) 591-597.
- Baclaski, J., Klei, H., Talbot, D., Lawton, C.W. (1991). Construction of Repetitive Polypeptides for Optical Applications. Abstracts of Papers of the American Chemical Society, 202.
- Bunning, T.J., Lawton, C.W., Klei, H.E., Sundstrom, D.W. (1991). Physical Property Improvements of a Pellicular Biocatalyst. Bioprocess Engineering, 7(1-2).
Selected Intellectual Property
- Patent - Lawton, C., Swartz, R."A Process for the Purification of Acarboseo," 99/07720
- Patent - Lawton, C.W., Conroy, S."Biomolecular Synthesis of Quantum Dot Composites," 6,350,515 United States
- Patent - Lawton, C.W."Biomolecular Synthesis of Quantum Dot Compositions," 5,985,353 United States
- Patent - Sanchez, J.D., Pommet, D., Fiddy, M., Lawton, C."On-Axis spatial light modulators and methods of use," 5,872,648 United States
- - Lawton, C.W., Nicolosi, R.J., McCarthy, S."Refined Vegetable Oils and Extracts Thereof," 6,197,357 United States
- Patent - Lawton, C.W."Biomolecular Synthesis of Quantum Dot Composite," 6,350,515 United States
- Patent - Lawton, C.W."Refined Vegetable Oils and Extracts Thereof," 6,197,357 United States
- Patent - Lawton, C.W."A Process for the Purification of Acarbose," 99/07720 United States
- Patent - Lawton, C.W."Biomolecular Synthesis of Quantum Dot Compositions," 5,985,353 United States
- Patent - Lawton, C.W."On-Axis spatial light modulators and methods of use," 5,872,648 United States
Selected Contracts, Fellowships, Grants and Sponsored Research
- (), Grant -
Lawton, C. - Purification Process Development for the Capture and Purification of MU1140 from (2014), -
Lawton, C.W. (Principal) - High Stable Human Plasma Butyrylcholinesterase for Intra-Muscular Delivery (2013), Contract - Defense Threat Reduction Agency
Lawton, C.W. (Co-Principal) - Preparation of E. coli Lysate (2012), -
Lawton, C.W. (Principal) - Preparation of IgG from HEK 293 I (2013), -
Lawton, C.W. (Principal) - Purification of StxB-cys (2012), -
Lawton, C.W. (Principal) - Purification Process Development for the Capture and Purification of MU1140 from (2013), -
Lawton, C.W. (Principal) - Production of E. coli Cell Paste II (2013), -
Lawton, C.W. (Principal) - Mixing Trial I (2012), -
Lawton, C.W. (Principal) - Capture Step of "FluBlok" with high capacity membrane adsorbers (2012), -
Lawton, C.W. (Principal) - New Faculty Position in Biomanufacturing Science and Engineering (2008), Grant -
Lawton, C.W. (Principal) - MicroFluidizer Use (2011), -
Lawton, C.W. (Principal) - Production of E coli Cell Paste (2012), -
Lawton, C.W. (Principal) - Developing Emergency Evacuation Plans for Nuclear Power Plants based on Large Scale Transportation Network Simulation (2011), - National Nuclear Security Administration
Laston, C., Xie, Y., Gartner, N. - Performance Enhancement of Traffic Operations Centers (2009), Grant - MassDOT Highway Division
Lawton, C.W., Gartner, N. - Production of Protein StxB/Cys (2009), -
Lawton, C.W. (Principal) - Development of a High-Capacity and Cost-effective Manufacturing Process for Chlor (2011), - U.S. Department of the Army
Lawton, C.W. (Principal) - Bioengineering of Saccharomyces cerevisiae for the Selective Production of beta-Penine (2011), - Naval Air Warfare Center
Lawton, C.W. (Principal) - Xylan to Itaconic Acid (2010), Contract - U.S. Department of Agriculture
Lawton, C.W. (Principal) - Production of Protein STxB/Cys (2009), -
Lawton, C.W. (Principal) - Shiga Scale-up (2010), -
Lawton, C.W. (Principal) - Fermentation Process Development With Single-Use Bioreactors (2009), -
Lawton, C.W. (Principal) - Interactive TMC Decision Support Tool Combining Simulation and Optimization (2008), Grant - UMass-University Transportation Center
Lawton, C.W., Gartner, N., Jones, L. - MicroFluidizer Use (2008), -
Lawton, C.W. (Principal) - Optimization and Scale-up of Natrix Q Membrane (2009), -
Lawton, C.W. (Principal) - Recombinant Antibody Productivity and Quality as a Function of Media Composition (2009), -
Lawton, C.W. (Principal) - Ozone-based Clean-in-place (CIP) of Bioreactors (2009), -
Lawton, C.W. (Principal) - GSP Production of Shiga StxB-cys-2 (2008), Grant -
Lawton, C.W. (Principal) - Traffic Flow Characteristics on Arterial Streets and their Impact on Capacity and Level of Service (2005), Grant - University Transportation Center, Region 1, U.S. Department of Transportation
Lawton, C.W., Gartner, N. - Implementation of a Web-Based Course on Traffic Principles for Intelligent Transportation Systems (2003), Grant - University Transportation Center, Region 1, U.S. Department of Transportation
Lawton, C.W. - Development of a Web-Based Course on Traffic Principles for Intelligent Transportation Systems (2001), Grant - University Transportation Center, Region 1, U.S. Department of Transportation
Lawton, C.W. - Development of Modules for a web based ITS Training and Education course (1999), Grant - University of Maryland
Lawton, C.W. - Evaluation of the Massachusetts Motorist Assistance Program (1995), Grant - Massachusetts Highway Department
Lawton, C.W., Gartner, N. - Real Time Traffic Adaptive Signal Control System (1993), Grant - U.S. Department of Transportation, Federal Highway Administration
Lawton, C.W., Gartner, N. - Development and Evaluation of Advanced Traffic Control Strategiesion (1993), Grant - Raytheon Company
Lawton, C.W. - Project # 05-05744 (1990), Sponsored Research - K-Tec Corporation
Kumar, J., Lawton, C.W. (Supporting)