Description

The course introduces students to the basic principles and mechanisms of toxicology with a focus on occupational and environmental health. Concepts of dose, dose rate, dose-response analysis, and test systems are presented in the context of the toxicology of major organ systems and toxic agents. The course covers toxicology of major organ systems (respiratory, dermal, immunologic, cardiovascular, neurological, reproductive systems, and cancers), major classes of contaminants (airborne particles, respirable fibers, vapors/gases, heavy metals, organic solvents, pesticides, sensitizers, emerging contaminants), and their mechanisms of action. A review of the necessary human biology and biochemistry of life is also provided.