Description

An in depth discussion of contemporary topics related to reproduction and embryogenesis. Lecture material is supplemented with reading assignments in a recently published textbook and current literature taken from research journals. Emphasis is on the dynamic nature of the interactions between developing cells as well as the events that occur during fertilization, implantation and the development of the mammalian embryo which lead to birth. Students examine how studies with nonmammalian model systems such as Drosophila and Xenopus have enhanced our knowledge of mammalian development. Among the topics discussed are the role of adhesion molecules, HOX genes, apoptosis, hypornethylation of genes, axis formation and hormonal control of differentiation. Class participation is expected. Critical scientific reading and thinking is encouraged by having students present to the class published original research papers on topics of current interest in the field of developmental biology.