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The purpose of this introductory course in the pharmaceutical sciences is to provide an overview of the drug development process, involving drug discovery, drug action, and drug delivery. The student will become acquainted with cutting-edge research in discovery, action, and delivery. This course provides a foundation in pharmaceutical sciences along with theoretical, practical, regulatory, and professional issues in the pharmaceutical sciences.
The purpose of this introductory course in the pharmaceutical sciences is to provide an overview of the drug development process, involving drug discovery, drug action, and drug delivery. Laboratory experiments will be performed to exemplify and expand upon the principles covered in Principles of Pharmaceutical Sciences lecture.
This course focuses of the study of the biochemical and physiological effects of drugs and the mechanisms of their actions. The quantitative aspects of drug absorption, distribution, metabolism, and excretion will be explored. The philosophy of pharmacokinetic modeling and its application in practice will be introduced.
Pre-req: PHRM.6100 Principles of Pharmaceutical Sciences.
This course explores research methodologies and statistics that are commonly used in pharmaceutical research. Scientific integrity in research will be discussed, as well as ethical issues in conducting pharmaceutical research in the laboratory.
Students in this course learn about modern analytical methods used to analyze the purity, strength, and quality of drugs and pharmaceutics.
The biological, biophysical and chemical factors that influence drug delivery systems will be analyzed. Principles of cellular drug transport, in vivo drug transport, and modern drug delivery, including drug targeting will be explored. The course will also address membrane trafficking and intracellular transport and the utilization of these mechanisms in drug delivery and targeting.
Pre-Req: Graduate level or Instructor permission.
Students in this course analyze the purity, strength, and quality of drugs and pharmaceutics by applying modern analytical methods. Raw materials and completed dosage forms will also be analyzed in the laboratory.
Co-req: PHRM.6400 Pharmaceutical Analysis.
Drug discovery is the translational application of biology, chemistry, medicine, business and law in the identification of new medicines. This course is designed to provide each student with a full understanding of the challenges and opportunities that face scientists engaged in this enterprise in the biotech and pharmaceutical industries. Active learning objectives (case studies; project team work0 are included to supplement the more didactic course materials, and to provide a simulation of the approaches used in industry to accomplish the key goal-the nomination of a clinical drug candidate worthy of extensive investment and testing in humans.
This course focuses of the study of the biochemical and physiological effects of drugs and the mechanisms of their actions. The quantitative aspects of drug absorption, distribution, metabolism, and excretion will be explored. The philosophy of pharmacokinetic modeling and its application in practice will be introduced. An overview of the structure, function and regulation of major drug metabolic enzymes and transporters will also be emphasized.
Pre-req: PHRM.6100 Principles of Pharmaceutical Sciences, and Graduate Level, or Permission of Instructor.
An independent study or laboratory project which has been approved and is under the direction of the project advisor. Projects are approved by the graduate coordinator I conjunction with the project advisor. "Variable credit course, student chooses appropriate amount of credits when registering."
This course provides an overview of the structure, function and regulation of major drug metabolic enzymes and transporters.
Select advanced topics and the evaluation of scientific literature in pharmaceutical sciences will be discussed in this seminar.
Enrolled students will be completing supervised research as they progress toward the completion of their degree. "Variable credit course, student chooses appropriate amount of credits when registering."
Enrolled students anticipate completion of all dissertation requirements during the semester in which they are enrolled for this course. "Variable credit course, student chooses appropriate amount of credits when registering."